Studies have shown that some aquatic plants and algae contain considerable levels of taurine, contrary to terrestrial plants. According to the university of California Davis, mackerel contain around 9.3g of taurine per kilogram. Fish are another source of food that contain high levels of taurine, including other marine animals – such as several crustacean species. Beef liver, for example, contains approximately 2.4g of taurine per kilogram. Animal meat is relatively rich in taurine, ranging from larger animals to smaller birds and insects. Foods that contain adequate levels of taurine include animal meat, fish and sea algae. Anxiety, autism, hypertension, gout, infertility and obesity may be conditions of low taurine levels. It is therefore necessary to include foods rich in taurine in our diets. Taurine, which is synthesized by combination of cysteine and methionine, is important in ensuring liver health, proper digestion and efficient metabolic processes within our bodies. Bile acid moiety is transferred from acyl-CoA thioester to taurine or glycine, forming N-acyl bile acid conjugate by bile acid-CoA:amino acid N-acyltransferaseĪccording to studies, taurine also functions to increase bile flow, bile acid pool size and rate of excretion of bile acids, while reducing the secretion rate of cholesterol in bile.The enzyme cholyl-CoA synthetase catalyzes bile acid into acyl-CoA thioester.Bile acid conjugation with taurine or glycine is catalyzed by two biochemical reactions: Therefore, bile acids are frequently found conjugated with taurine – enabling advanced hepatocyte efficiency. For instance, membrane mobility, and overall fluidity of hepatocytes, increase in the presence of bile acids conjugated with taurine. Bile acids and conjugation with taurineĪs bile acids are conjugated with taurine in the liver, there are several modifications that occur in hepatocytes that are vital to ensure the liver remains in a healthy state. Since sodium is involved in bile salt synthesis and reabsorption, it is clear that bile salts and bile acids are regularly and rapidly converted to maintain bile production.įurther, since there is an apparent link between bile salts and bile acids, and there exists a conjugation of bile acids with taurine, there is proof that taurine is necessary for the conversion between bile salts and bile acids – along with conjugation of bile acids and continued circulation of bile and its derivatives, such as in enterohepatic circulation. In addition, large amounts of bile salts are reabsorbed in the gut and recycled for further bile production. Taurine is therefore responsible for providing a substrate for bile salts. Taurine, an amino acid that affects hepatocytes, is involved in forming bile salts from bile acids through conjugation i.e binding. Taurine provides a substrate for bile salts It is also important to consider which foods help to increase taurine concentrations and thus assist bile production and synthesis. Furthermore, bile acids, which function to digest lipids, are conjugated with taurine – increasing membrane mobility and fluidity of hepatocytes. Therefore, taurine is paramount in the process of the formation of bile salts, and ultimately, bile. Several bile salts are formed by the conjugation of taurine with bile acids in the liver, as taurine provides a substrate for bile salts. Bile acids and bile salts, however, are synthesized in the liver via specific biochemical reactions for bile to be formed as a final product. Bile and its constituents are produced by the liver and stored in the gall bladder. ‘Your Baby’: Pregnancy Ready Course (Paid)īile, which consists mainly of bile acids and bile salts, aids digestion in the small intestine.Foundations Training Course (Methyl + Genomics).Join the Methylation & Genomics Institute. Find An MTHFR Institute Trained Practitioner.Chemical Sensitivity, Chronic Fatigue & Fibromyalgia.Package Option – Book A Fertility Consult.Chemical Sensitivity, Fatigue & Fibromyalgia.What is MTHFR & Methylation Disturbances.
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